abstract：BACKGROUND:The effects of intestinal inflammation on the central nervous system are unknown. The dorsal motor nucleus of the vagus (DMNV) integrates peripheral and central signals and sends efferent signals to the gastrointestinal system. The purpose of this study was to determine the effects of intestinal inflammation...

journal_title：Surgery

authors： Ammori JB,Zhang WZ,Li JY,Chai BX,Mulholland MW

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:In living donor liver transplantation, variations in donor vascular anatomy, recipient portal vein thrombosis, short donor vessel length, and reconstitution of the anterior sector outflow in right lobe grafts often make complex and innovative vascular reconstructions necessary, which require the use of exten...

journal_title：Surgery

authors： Kakodkar R,Nundy S,Soin AS

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:General, health-related quality-of-life questionnaires and recovery-specific questionnaires have been used to measure recovery in surgical patients. The aim of this study was to evaluate the clinimetric properties of 3 recovery instruments and to examine whether recovery-specific instruments are useful. MET...

journal_title：Surgery

authors： Kluivers KB,Hendriks JC,Mol BW,Bongers MY,Vierhout ME,Brölmann HA,de Vet HC

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Identification of recurrent laryngeal nerve (RLN) has decreased the rates of permanent RLN palsy during thyroid operations; however, unexpected RLN palsy still occurs, even though the visual integrity was assured and most nerve injuries were not recognized intraoperatively. The aim of this study is to determ...

journal_title：Surgery

authors： Chiang FY,Lu IC,Kuo WR,Lee KW,Chang NC,Wu CW

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The development of fulminant Clostridium difficile colitis (FCDC) requires prompt operative intervention and is associated with a high mortality rate. The aim of this study was to use a case-control design to define the clinical and laboratory parameters that predict which patients with Clostridium difficile...

journal_title：Surgery

authors： Greenstein AJ,Byrn JC,Zhang LP,Swedish KA,Jahn AE,Divino CM

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Cognitive impairment was frequently reported in uremic patients with dialysis, but improvements of cognition after parathyroidectomy for symptomatic secondary hyperparathyroidism have never been reported before. METHODS:Thirty-nine patients, who were successfully operated on with total parathyroidectomy plu...

journal_title：Surgery

authors： Chou FF,Chen JB,Hsieh KC,Liou CW

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Hepatectomy for colorectal liver metastases (CRLM) may offer good long-term survival. The impact of the tumor-free surgical margin on long-term results remains controversial, and we have assessed this component in 185 patients. METHODS:Between 1992 and 2005, 185 patients underwent primary hepatectomy with c...

journal_title：Surgery

authors： Nuzzo G,Giuliante F,Ardito F,Vellone M,Giovannini I,Federico B,Vecchio FM

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Heparin binding to platelet factor 4 (PF4) generates a new antigenic epitope. In an unpredictable fashion, as many as approximately 17% of patients treated with unfractionated heparin (UFH) and approximately 8% treated with low-molecular-weight heparin (LMWH) subsequently develop the anti-heparin-PF4 antibod...

journal_title：Surgery

authors： Baldwin ZK,Spitzer AL,Ng VL,Harken AH

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Acute respiratory failure is a common, life-threatening complication after severe trauma. Polymorphisms in cytokine genes, linked to cytokine inducibility, may influence the susceptibility to acute respiratory failure and serve as risk predictors. METHODS:This PROSPECTIVE cohort study (n = 100) included Cau...

journal_title：Surgery

authors： Schroeder O,Schulte KM,Schroeder J,Ekkernkamp A,Laun RA

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Ischemia-reperfusion injury of skeletal muscle is a common clinical and experimental problem. To date, there has been no uniform and reproducible method to assess the extent of histologic injury. In this study, we developed a novel statistical methodology for evaluating injury in individual myocytes and 3 di...

journal_title：Surgery

authors： McCormack MC,Kwon E,Eberlin KR,Randolph M,Friend DS,Thomas AC,Watkins MT,Austen WG Jr

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Solid pseudopapillary neoplasm of the pancreas is a distinctive pancreatic neoplasm with low metastatic potential. This study examines clinical differences and prognosis between male and female patients. METHODS:The medical records of 34 consecutive patients with pancreatic solid pseudopapillary neoplasms b...

journal_title：Surgery

authors： Machado MC,Machado MA,Bacchella T,Jukemura J,Almeida JL,Cunha JE

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Successful parathyroidectomy for sporadic primary hyperparathyroidism (pHPT) is predicted by a 50% drop in PTH intra-operatively. Vitamin D is a known inhibitor of PTH secretion and is associated with secondary HPT following adenoma resection. This study examined the impact of 25-hydroxyvitamin D (25OHD) def...

journal_title：Surgery

authors： Untch BR,Barfield ME,Dar M,Dixit D,Leight GS Jr,Olson JA Jr

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:The results of video-assisted thyroidectomy in a large series of patients with papillary thyroid carcinoma were evaluated, especially in terms of the completeness of the operative resection. METHODS:The medical records of all patients who underwent video-assisted total thyroid resection (single procedure to...

journal_title：Surgery

authors： Lombardi CP,Raffaelli M,de Crea C,Princi P,Castaldi P,Spaventa A,Salvatori M,Bellantone R

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Adrenal cortical carcinoma (ACC) is a rare disease in which recurrence after surgery is common. Mitotane is the primary systemic treatment for recurrent ACC; data are limited regarding the impact of mitotane on recurrent ACC. METHODS:We reviewed the records of all patients who underwent surgery for ACC eval...

journal_title：Surgery

authors： Gonzalez RJ,Tamm EP,Ng C,Phan AT,Vassilopoulou-Sellin R,Perrier ND,Evans DB,Lee JE

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:A breast cancer (BC) history was elicited more frequently than expected among thyroid operation patients, which prompted an investigation of risks for concurrent or subsequent nonendocrine malignancies. METHODS:Of 94,939 patients at a tertiary referral center with breast, thyroid, or parathyroid disease fro...

journal_title：Surgery

authors： Garner CN,Ganetzky R,Brainard J,Hammel JP,Berber E,Siperstein AE,Milas M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Secondary hyperparathyroidism (SHPT) and its associated abnormalities in mineral metabolism increase the risk of cardiovascular morbidity and death in chronic renal failure (CRF). The effect of parathyroidectomy (PTX) on the incidence of major cardiovascular events in CRF patients with SHPT is unknown. We te...

journal_title：Surgery

authors： Costa-Hong V,Jorgetti V,Gowdak LH,Moyses RM,Krieger EM,De Lima JJ

更新日期：2007-11-01 00:00:00

abstract：UNLABELLED:In patients undergoing pancreaticoduodenectomy (PD) for pancreatic adenocarcinoma (PC), conversion to total pancreatectomy (TP) may be necessary to achieve R0 resection. HYPOTHESIS:We sought to examine the oncologic benefit of conversion of PD to TP to achieve an R0 resection in patients with an isolated po...

journal_title：Surgery

authors： Schmidt CM,Glant J,Winter JM,Kennard J,Dixon J,Zhao Q,Howard TJ,Madura JA,Nakeeb A,Pitt HA,Cameron JL,Yeo CJ,Lillemoe KD

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Hemorrhage-induced activation of endothelial cell Na+/H+ -exchanger results in cellular swelling, which physically impedes capillary filling and compromises gut perfusion. We hypothesized that correction of the vascular volume deficit by conventional resuscitation does not improve capillary filling unless ce...

journal_title：Surgery

authors： Zakaria el R,Li N,Matheson PJ,Garrison RN

更新日期：2007-10-01 00:00:00

abstract：:Two cases are reviewed here that highlight the utility of minimally invasive surgery (MIS) techniques in major surgery procedures involving the liver. They also demonstrate specific operative procedures once thought beyond the scope of the MIS surgeon, but they are now standard in expert hands. Improved methods for at...

journal_title：Surgery

authors： Saxton ML

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Small intestinal submucosa (SIS) represents a novel bio-scaffolding material that may be used to repair hollow-organ defects. However, it is unclear whether neurophysiologic responses return to SIS-grafted areas in the gut. We evaluated the functional recovery of a stomach defect grafted with the porcine-der...

journal_title：Surgery

authors： Ueno T,de la Fuente SG,Abdel-Wahab OI,Takahashi T,Gottfried M,Harris MB,Tatewaki M,Uemura K,Lawson DC,Mantyh CR,Pappas TN

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Service and education activities have not been well defined or studied. The purpose of this study is to describe how attendings and residents categorize common resident activities on a service-education continuum. METHODS:A web-based survey was designed to categorize resident activities. A panel of resident...

journal_title：Surgery

authors： Reines HD,Robinson L,Nitzchke S,Rizzo A

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Cholecystosteatosis is the accumulation of gallbladder wall fats leading to decreased gallbladder emptying. Ezetimibe inhibits intestinal fat absorption and prevents murine gallstone formation. However, the influence of ezetimibe on gallbladder emptying and cholecystosteatosis has not been studied. Therefore...

journal_title：Surgery

authors： Mathur A,Walker JJ,Al-Azzawi HH,Lu D,Swartz-Basile DA,Nakeeb A,Pitt HA

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:We hypothesized that acetylation of the Stat1 regulates interferon-gamma (IFN-gamma) mediated macrophage expression of inducible nitric oxide synthase (iNOS). METHODS:RAW 264.7 iNOS expression was induced with IFN-gamma. Deacetylase inhibitors trichostatin A (TSA) or valproic acid (VPA) were added. Stat1 an...

journal_title：Surgery

authors： Guo L,Guo H,Gao C,Mi Z,Russell WB,Kuo PC

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Intraoperative parathyroid hormone (IOPTH) monitoring is well-established in operation for primary hyperparathyroidism (HPT). In diseases where total parathyroidectomy (tPx) is a treatment option its reliability to predict postoperative residual parathyroid hormone (PTH) remains in question. METHODS:Thirty-...

journal_title：Surgery

authors： Müller-Stich BP,Brändle M,Binet I,Warschkow R,Lange J,Clerici T

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:In thoracic esophageal cancer, lymph node metastases distribute widely from the neck to the abdominal area as a result of a complex periesophageal lymphatic network. The aim of the present study was to evaluate the potential clinical utility of a new method of mapping lymphatic drainage from tumors using fer...

journal_title：Surgery

authors： Motoyama S,Ishiyama K,Maruyama K,Okuyama M,Sato Y,Hayashi K,Nanjo H,Saito H,Minamiya Y,Ogawa J

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Although various suture techniques for murine pancreas transplantation have been described, severe limitations have limited their widespread use. We therefore designed a surgical model for cervical heterotopic pancreas transplantation using a cuff technique. METHODS:C57BL6 mice were used as donor and recipi...

journal_title：Surgery

authors： Maglione M,Hermann M,Hengster P,Schneeberger S,Mark W,Obrist P,Margreiter R,Brandacher G

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The presence or absence of lymph node metastases is known to be an important prognostic factor for patients with pancreatic cancer. Few studies have investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard...

journal_title：Surgery

authors： Pawlik TM,Gleisner AL,Cameron JL,Winter JM,Assumpcao L,Lillemoe KD,Wolfgang C,Hruban RH,Schulick RD,Yeo CJ,Choti MA

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:We carried out a prospective, randomized, 4-arm study including control arm, blinding of examiners to determine effectiveness of computer-based video instruction (CBVI) and different types of expert feedback (concurrent and summary) on learning of a basic technical skill. METHODS:Using bench models, partici...

journal_title：Surgery

authors： Xeroulis GJ,Park J,Moulton CA,Reznick RK,Leblanc V,Dubrowski A

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The development of liver failure significantly influences prognosis during the course of major septic complications. Although the underlying cause for septic liver failure is still unclear, research using animal models has demonstrated that an increased nitric oxide (NO) synthesis compromises detoxification ...

journal_title：Surgery

authors： Novotny AR,Emmanuel K,Maier S,Westerholt A,Weighardt H,Stadler J,Bartels H,Schwaiger M,Siewert JR,Holzmann B,Heidecke CD

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The management of splenic injuries has evolved with a greater emphasis on nonoperative management. Although several institutions have demonstrated that nonoperative management of splenic injuries can be performed with an increasing degree of success, the impact of this treatment shift on outcome for all pati...

journal_title：Surgery

authors： Harbrecht BG,Zenati MS,Ochoa JB,Puyana JC,Alarcon LH,Peitzman AB

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Operative resection is the only curative treatment for patients with pheochromocytomas, paragangliomas, and other catecholamine-producing neoplasms. Activation of glycogen synthase kinase 3beta (GSK3beta) is thought to promote tumor growth and neuroendocrine (NE) peptide secretion in NE neoplasms. Thus, we h...

journal_title：Surgery

authors： Kappes A,Vaccaro A,Kunnimalaiyaan M,Chen H

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Aggressive screening for blunt cerebrovascular injury (BCVI) and prompt anticoagulation for documented injuries has resulted in a significant reduction in ischemic neurologic events. An association between vertebral artery injuries (VAIs) and specific cervical spine fracture patterns has been suggested; howe...

journal_title：Surgery

authors： Cothren CC,Moore EE,Ray CE Jr,Johnson JL,Moore JB,Burch JM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Four-dimensional computed tomography (4D-CT) provides both functional and highly detailed anatomic information about parathyroid tumors. The purpose of this study was to compare 4D-CT with sestamibi imaging and ultrasonography as methods for the accurate preoperative localization of hyperfunctioning parathyr...

journal_title：Surgery

authors： Rodgers SE,Hunter GJ,Hamberg LM,Schellingerhout D,Doherty DB,Ayers GD,Shapiro SE,Edeiken BS,Truong MT,Evans DB,Lee JE,Perrier ND

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Adrenal venous sampling (AVS) is used in the workup of primary hyperaldosteronism (PA). The purpose of this study was to determine the success rate of AVS and to examine the decision-making process after "less than ideal" AVS. METHODS:A total of 60 patients underwent 62 AVS for PA. Biochemical evidence of a...

journal_title：Surgery

authors： Harvey A,Kline G,Pasieka JL

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Thoracopancreatic fistula is a rare clinical entity but a serious complication of inflammatory pancreatic diseases, caused by a disruption of the pancreatic ductal system. Its diagnosis is frequently misleading, however, and thus is often delayed. METHODS:Seven patients with thoracopancreatic fistula who pr...

journal_title：Surgery

authors： Tajima Y,Tsutsumi R,Kuroki T,Mishima T,Adachi T,Kitasato A,Kanematsu T

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to review our 15-year experience in the treatment of blunt splenic injury in adults. Our hypothesis was that the implementation of a change in practice, with stress on splenic preservation and splenic artery embolization for the management of splenic injury, would result in impr...

journal_title：Surgery

authors： Rajani RR,Claridge JA,Yowler CJ,Patrick P,Wiant A,Summers JI,McDonald AA,Como JJ,Malangoni MA

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:The goal of the current study is to characterize the presentation, therapy, and outcomes of acute limb ischemia (ALI) associated with type B aortic dissection (AoD). METHODS:The prospective/retrospective International Registry for Acute Aortic Dissection (IRAD) database and a single institutional database w...

journal_title：Surgery

authors： Henke PK,Williams DM,Upchurch GR Jr,Proctor M,Cooper JV,Fang J,Nienaber CA,Isselbacher EM,Fattori R,Dasika N,Gemmete J,Stanley JC,Wakefield TW,Eagle KA

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:We determined whether hepatic intra-arterial infusion of 5-fluorouracil (5-FU) in patients with synchronous hepatic metastases from colorectal cancer, in whom the primary lesion was resectable but hepatic metastatic lesions were non-resectable helped improve survival time when administered on the basis of the...

journal_title：Surgery

authors： Matsuoka H,Nagaya M,Tsukikawa S,Yanagi Y,Isogai A,Kubota S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:In the developmental stage, pancreas derives from the endodermal cells where the transcription factor, pancreatic duodenal homeobox gene-1 (pdx-1) is expressed. In adulthood, pdx-1 expression is localized to pancreatic beta cells, which is necessary for maintenance of beta cell function. Recently, ectopic ex...

journal_title：Surgery

authors： Koizumi M,Nagai K,Kida A,Kami K,Ito D,Fujimoto K,Kawaguchi Y,Doi R

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PRO) reflect the functional outcomes of inguinal herniorrhaphy. We studied the effect of hernia recurrence and complications on PRO for participants in the Veterans Affairs trial of Open or Laparoscopic Repair of Inguinal Hernia. METHODS:Analyzed PRO included (1) the Medical Outco...

journal_title：Surgery

authors： Hawn MT,Itani KM,Giobbie-Hurder A,McCarthy M Jr,Jonasson O,Neumayer LA

更新日期：2006-08-01 00:00:00